ErgoPharm, the hormone authority and creator of 1-AD?, has now developed the most effective natural compound to combat estrogen - 6-OXO? 6-OXO? contains a naturally occurring aromatase inhibitor that is devoid of any direct hormonal or prohormonal activity (androgenic or estrogenic). It is what science refers to as a "suicide inhibitor" of aromatase. Specifically this means that it will irreversibly bind to the aromatase enzyme and permanently deactivate it. With prolonged use of 6-OXO the result will be a very substantial reduction in the production of estrogen in the body, along with a coinciding up-regulation of natural (testicular) testosterone production.